Caffeine is still the most intense stimulant. “It blows the others out of the water,” says Crystal Haskell-Ramsay, a nutritional psychologist at Northumbria University in England. But caffeine doesn’t act alone. Tea, for example, contains the amino acid theanine. In 2008, Haskell-Ramsay showed that subjects who took large doses of caffeine and theanine together felt more alert than if they had taken them separately. The subjects also had better reaction time and working memory. A follow-up using smaller doses, comparable to the amount in a cup of tea, found the opposite: Theanine killed the caffeine buzz. “I think it’s dose-specific,” Haskell-Ramsay says. Still, not everyone feels the same energy jolt from a given beverage. “There are genetic differences in how people respond,” Haskell-Ramsay says. She, for one, avoids coffee. “It’s too stimulatory for me,” she says. That is, unless she’s desperate. “I was at a conference once, and the tea was terrible. By day four or five, I was so caffeine-deprived, I finally bit the bullet and ordered a cappuccino.” This article was originally published in the October 2015 issue of Popular Science.